中文簡介

金屬組學發表前沿研究，旨在闡明金屬和金屬化合物在生物系統中的識別、分布、動力學、作用和影響。針對細胞、組織、有機體和各種環境生態位中這些無機元素的“什么、在哪里、何時、如何和為什么”的研究是受歡迎的，特別是那些采用來自分析、生物無機、醫學、環境、生物物理、細胞生物學、植物生物學和化學生物學社區的多學科方法的研究。我們特別感興趣的是那些增強我們對金屬依賴生命過程的分子機制的化學和/或物理理解的文章，以及那些探索金屬組學和其他組學方法之間的共同空間的文章，以揭示對生物過程的新見解。在2019年我們慶祝成立10周年之際，金屬組學試圖將自己定位于分析化學前沿，這些進展注定會闡明生物系統的巨大復雜性。因此，我們特別歡迎那些概述尖端分析技術的論文，例如在發展和應用強大的新成像、光譜和質譜方法方面。還強烈鼓勵對復雜系統或作為微環境功能的金屬形態、販運和動力學的新見解的工作。研究金屬依賴過程與機體健康或疾病相關的系統級反應之間的相互聯系也受到強烈鼓勵，例如，研究化學暴露對金屬穩態的影響或金屬藥物對細胞過程的影響。作者被要求使用“對金屬組學的意義”的聲明，在提交所有手稿時要求，作為一種機制，以突出這些跨學科的進展，在生物學和金屬組學社區的意義。

　　英文簡介

Metallomics publishes cutting-edge investigations aimed at elucidating the identification, distribution, dynamics, role and impact of metals and metalloids in biological systems. Studies that address the “what, where, when, how and why” of these inorganic elements in cells, tissues, organisms, and various environmental niches are welcome, especially those employing multidisciplinary approaches drawn from the analytical, bioinorganic, medicinal, environmental, biophysical, cell biology, plant biology and chemical biology communities. We are particularly interested in articles that enhance our chemical and/or physical understanding of the molecular mechanisms of metal-dependent life processes, and those that probe the common space between metallomics and other ‘omics approaches to uncover new insights into biological processes.As we celebrate our 10-year anniversary in 2019, Metallomics seeks to position itself at the forefront of those advances in analytical chemistry destined to clarify the enormous complexity of biological systems. As such, we particularly welcome those papers that outline cutting-edge analytical technologies, e.g., in the development and application of powerful new imaging, spectroscopic and mass spectrometric modalities. Work that describes new insights into metal speciation, trafficking and dynamics in complex systems or as a function of microenvironment are also strongly encouraged. Studies that examine the interconnectivity of metal-dependent processes with systems level responses relevant to organismal health or disease are also strongly encouraged, for example those that probe the effect of chemical exposure on metal homeostasis or the impact of metal-based drugs on cellular processes.Authors are asked to use the Statement on the “Significance to Metallomics”, required upon submission of all manuscripts, as a mechanism to highlight these interdisciplinary advances of significance to the metals in biology and metallomics communities.

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