中文簡介
突變研究綜述的主題領域包括突變研究及其應用的整個科學領域,特別強調突變與疾病的關系。因此,本節(jié)將介紹人類基因組研究的進展(包括變異檢測和功能基因組學的進化技術),以及在臨床遺傳學、基因治療和相關環(huán)境因素健康風險評估中的應用。遺傳毒理學和環(huán)境誘變(包括調節(jié)環(huán)境因子遺傳活性的因子)將繼續(xù)成為本節(jié)的重點。除了完整的評論外,還將發(fā)布關于特定主題的小評論。
英文簡介
The subject areas of Reviews in Mutation Researchencompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus this section will cover advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concern. Genetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section. In addition to full-length reviews, mini-reviews on specific topical themes will be published.
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